Measure 3 tablespoons chili powder, 1 tablespoon ground cumin, 1 tablespoon smoked paprika, 1 teaspoon garlic powder, 1 teaspoon onion powder, 1 teaspoon dried oregano, ½ teaspoon salt, ¼ teaspoon black pepper, and ¼ teaspoon cayenne pepper (optional) into a small bowl.
Stir vigorously until all spices are completely combined and the color is uniform throughout.
Transfer the seasoning blend to an airtight container and store in a cool, dark place for up to 6 months.